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NXL103 publications
List of all publications on
avibactam
(NXL104)
2009
JAC
In vitro
activity of the ß-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases
2009
ICAAC
Effect of Age and Gender on the Pharmacokinetics (PK) and Safety of NXL104 in Healthy Subjects (Protocol NXL104/1004)
2009
ICAAC
The Nature of Inhibition of TEM-1 ß-Lactamase by the Non-ß-Lactam Inhibitor NXL104
2009
ICAAC
Activity of Ceftazidime / NXL104 and Select Comparators against Geographically Diverse Clinical Isolates of
Pseudomonas aeruginosa
2009
ICAAC
Pharmacokinetics (PK) and Efficacy of Ceftazidime (CAZ) / NXL104 combination in a Murine Pneumonia Model Caused by an AmpC-Producing
Klebsiella pneumoniae
2009
ICAAC
In Vitro
Antibacterial Activity of Ceftazidime (CAZ) in Combination with the ß-Lactamase Inhibitor, NXL104
2009
ICAAC
Efficacy of Ceftazidime (CAZ) /NXL104 Combination in Murine Septicaemia Caused by CTX-M-Producing
Enterobacteriaceae
species
2009
ICAAC
Anti-Anaerobic Activity of NXL104 in Combination with ß-lactams and Metronidazole
2009
ICAAC
High Resolution Crystal Structure of CTX-M-15 in Complex with the New ß-lactamase Inhibitor NXL104
2009
ICAAC
In Vitro
Activity of NXL104/Ceftazidime Against ß-Lactamase Producing Anaerobic Bacteria
2009
ICAAC
Efficacy of NXL104 in combination with ceftazidime in murine infection models
2009
ECCMID
Use of the Hollow Fibre Infection Model in the Pharmacodynamic evaluation of the Beta-lactamase Inhibitor NXL104
2008
Superbugs
Ceftazidime / NXL104, an alternative to the use of carbapenems in the treatment of Gram-negative infections
2008
RICAI
Activité
in vitro
de NXL104 sur CTX-M-15 et KPC-2 : un nouvel inhibiteur de ß-lactamases à spectre étendu (BLSE) et de carbapénèmases de classe A
2008
JAntimicChemother
NXL104 combinations versus Enterobacteriaceae with CTX-M extended-spectrum ß-lactamases and carbapenemases
2008
ICAAC
Use of NXL104, a ß-lactamase Inhibitor, to Detect
Klebsiella pneumoniae
Carbapenemase (KPC) in
Enterobacteriaceae
2008
ICAAC
Importance of NXL104 Pharmacokinetics (PK) in the Pharmacodynamics (PD) of Ceftazidime+NXL104 Combinations in an
in vitro
Hollow Fiber Infection Model
2008
10th BLA Meeting
In vitro
activity of the ceftazidime / NXL104 combination against
Pseudomonas aeruginosa
clinical isolates
2007
ICAAC
Activity of the New ß-Lactamase Inhibitor NXL104 against KPC ß-Lactamases
2007
ICAAC
In vitro
Activity of the New ß-lactamase Inhibitor NXL104 : Restoration of Ceftazidime (CAZ) Efficacy Against Carbapenem-Resistant
Enterobacteriaceae
Strains
2007
ICAAC
Safety, Single Dose Pharmacokinetics, and Pharmacodynamics of ß-Lactmase Inhibitor NXL104 in Healthy Young Male Adults
2007
ICAAC
NXL104 / Cephalosporin Combinations vs.
Enterobacteriaceae
with CTX-M ESBLs
2007
ICAAC
Pharmacokinetics of the New ß-Lactamase Inhibitor NXL104 in an Experimental Rabbit Meningitis Model; Restoration of the
Bacteriological Efficacy of Ceftazidime (CAZ) against a Class C Producing
K. pneumoniae
2007
ECCMID
The Efficacy of Ceftazidime combined with NXL104, a novel ß-lactamase inhibitor, in a mouse model of
kidney infections induced by ß-lactamase producing Enterobacteriaceae
2007
CHI
NXL104 ß-lactamase inhibitor
2006
RICAI
Activité
in vitro
de NXL104 sur SHV-4: un nouvel inhibiteur des ß-lactamases à spectre étendu
2006
RICAI
Etude de l'expression d'AmpC dans Enterobacter cloacae : absence de risque d'induction avec l'nhibiteur de ß-lactamases NXL104
2006
ICAAC
What's in the Pipeline?
2006
ICAAC
The ß-lactamase Inhibitor NXL104 Does Not Induce
ampC
ß-lactamase Expression in
Enterobacter
cloacae
:
Evaluation of ampC Expression by Quantitative Polymerase Chain Reaction (Q-PCR).
2006
ICAAC
NXL104, a Novel ß-lactamase Inhibitor, Restores the Bactericidal Activity of Ceftazidime Against ESBL and AmpC Producing Strains of
Enterobacteriaceae
2005
ICAAC
Safety and Toxicokinetics of NXL104, a Broad Spectrum ß-lactamase Inhibitor, in the Rat
2005
ICAAC
Efficacy of NXL104, a Novel Broad Spectrum ß-lactamase Inhibitor, in Combination with Ceftazidime in Murine Septicaemia and Pneumonia
2005
ICAAC
In vitro activity of NXL104 (formerly AVE1330A), a New ß-lactamase Inhibitor, in Combination with Cefpodoxime and Cefixime against 3rd Generation Cephalosporin-Resistant Isolates of species of the
Enterobacteriaceae
2005
ECCMID
In vitro activity of AVE1330A, a novel ß-lactamase inhibitor, in combination with aztreonam or ceftazidime against ceftazidime-resistant isolates of species of the
Enterobacteriaceae
2005
9th BLA MEETING
Clinical potential of the ß-lactamase inhibitor NXL104 (formerly AVE1330)
2004
JAntimicChemother
In vitro
activity of AVE1330A, an innovative broad-spectrum non-ß-lactam ß-lactamase inhibitor
This compilation was produced by Novexel SA, Romainville, France.